The Plantersville area of Georgetown County, SC incorporates the area east and west of the Plantersville Road loop between the Black/Pee Dee Rivers and Hwy 701. The area includes the Historic District of plantation homes and properties, four primarily African American villages (Annie Village, Jackson Village, St Paul’s and Plantersville) and an ecosystem of rivers, marshes, creeks and forest.

Plantersville Cultural Center is located at 7 Plantersville Road – at the beginning of the Plantersville Scenic By-way.